Clinically Proven to Reduce the Effects of Depression, Anxiety and ADHD, and Improve Learning Outcomes
Developed by World-leading Neuroscientists at Yale University
Below you will find 30 peer-reviewed research papers published in leading scientific journals that were authored by C8’s founder, Dr. Bruce Wexler and his colleagues at Yale University School of Medicine and around the world. These papers describe the technology that underlies our products and the successful clinical trials that have been run using the cognitive exercises in our products such as the “catch the ball” exercises that were the primary component of the intervention in the depression trials.
Blue text is for Adult Brain Health articles Red Text is for Child Brain Health and Learning articles
Surti TS, Vinogradov, S, Bell MD, Wexler BE. (2019 doi: 10.1016/j.schres.2019.11.021): Improvement on visual cognitive training exercises in schizophrenia is present but less robust than in healthy individuals. Schizophrenia Research
Kurtz, M.M., Seltzer, J.C., Shagan, D.S., Wexler, B.E. (2005, 31(2): 330-330): Neurocognitive remediation for patients with schizophrenia: How specific is the intervention and its effects? Schizophrenia Bulletin
Bell MD, Bryson GJ, Greig TC, Fiszdon JM, Wexler BE. (2005, 31(2): 518-519): Functional outcomes from a RCT of cognitive training and work therapy: 12 month follow-up. Schizophrenia Bulletin
Bryson GJ, Bell MD, Greig TC, Wexler BE. (2005, 31(2): 520-521): Neuropsychological outcomes from a RCT of cognitive training and work therapy: 12 month follow-up. Schizophrenia Bulletin
Founder and Chief Scientific Officer of C8 Sciences, is professor of psychiatry at Yale School of Medicine. In 45 years of neuroscience research, he has advanced the understanding of brain plasticity and been an international leader in developing computer-presented brain exercises to improve executive cognitive functions. His patent-pending innovations led to the development of the ACTIVATE™ cognition cross-training program for children that integrates computer-presented and physical exercises to improve executive function skills essential for learning. For this work, he received an NIH Director’s Award for “high innovation, high impact, paradigm-changing” research. Dr. Wexler’s book Brain and Culture: Neurobiology, Ideology, and Social Change (MIT Press; Chinese translation Zhejiang University Press)has received international attention. Oliver Sacks called it “a major achievement, touching the deepest biological and human issues…a very powerful and very important book.” Professor Howard Gardner of Harvard University School of Education called it “A pioneering and bold effort to construct a bridge between scientific findings about the brain and the diversity, strengths, and fragilities of human cultures.” Dr. Wexler has given multiple academic and public lectures in North and South America, Europe and Asia. He is a consultant for the Kennedy Foundation Forum on Technology and Mental Health Innovations and BrainFutures, and previously served as a consultant for the GE Brain Trust and the Gates Foundation.
Dr. Wexler graduated magna cum laude from Harvard University, studied psychiatry at Anna Freud’s Hampstead Clinic and Neurology at the Institute of Neurology, Queen’s Square, London. He received his Doctor of Medicine from Albert Einstein College of Medicine and training in psychiatry at Yale.