The Neuroscience Behind ACTIVATE™’s Super-Charged Brain Training
Meet Dr. Bruce Wexler
Research by renowned Psychiatric Neuroscientist, Dr. Bruce Wexler of Yale University, has advanced the understanding of neuroplasticity: the brain’s ability to reorganize itself by forming new neural connections. The human brain remains highly flexible for a much longer time after birth than the brains of any other animals, and Dr. Wexler realized that parts of the brain thought to be compromised in ADHD and associated with attention, response inhibition, and other executive functions actually continue to develop throughout childhood and adolescence. The programs have since proven to be beneficial for improving cognitive function for all children and not just those with learning disabilities.
With this in mind, Dr. Wexler created computerized cognitive remediation (CCRT), the foundation of what is now ACTIVATE™, which focused on strengthening those compromised parts of the ADHD brain and focused on working memory using spatial, digit, and word span exercises that increased in length as the child’s performance improved. In the initial randomized control trial of 53 children, the executive function and working memory of the treatment group showed dramatic improvement! An independent scientific study revealed that the benefits of Dr. Wexler’s CCRT program were significantly greater than the benefits of ADHD medication in a group of 25 children with the learning disorder.
In late 2011, Dr. Wexler’s work was recognized by the National Institutes of Health with their prestigious Transformative Research Award for “high innovation, high impact, paradigm-changing research with the potential to transform medical practice” which gave him the ability to help found the C8 Sciences company and fully develop ACTIVATE™.